Activating the Immune System to Fight COVID-19
CPI-006 is an immunomodulatory antibody that binds to immune cells, leading to activation of B cells and antibody production that we believe will destroy the SARS-CoV-2 virus.
This therapy has the potential to be used in mild or moderately ill COVID-19 patients as well as in healthy people to enhance the efficacy of vaccines.
Increasing the immune response to the COVID-19 infection may lead to faster viral clearance, shorter recovery time, less complications and longer lasting immunity
This approach has the potential to be a foundational therapy for SARS-CoV-2 mutant variants, other coronaviruses or future pandemics
COVID-19 Publications and Presentations
Gerard Criner, M.D., Chair & Professor, Thoracic Medicine & Surgery, Lewis Katz School of Medicine at Temple University
Oral presentation at the 2020 Society for Immunotherapy of Cancer (SITC) 35th Annual Meeting
Criner G1, Mobasher M2, Hill C2, Hu S2, Mahabhashyam S2, Brody J3, Marron T3, Willingham S2, Miller R2
1Temple University Hospital, Philadelphia, PA, USA; 2Corvus Pharmaceuticals Inc, Burlingame, CA, USA; 3Icahn School of Medicine at Mount Sinai, New York, NY, USA
Poster presentation at the 2020 Society for Immunotherapy of Cancer (SITC) 35th Annual Meeting
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Stephen B. Willingham, Gerard Criner, Craig Hill, Shenshen Hu, Jenny A. Rudnick, Barbara Daine-Matsuoka, Jessica Hsieh, Haider Mashhedi, Andrew N. Hotson, Joshua Brody, Thomas Marron, Emily Piccione, Joseph J. Buggy, Suresh Mahabhashyam, William B. Jones, Mehrdad Mobasher, and Richard A. Miller
medRxiv doi: 10.1101/2020.09.10.20191486