Manager, Process Chemistry

Department/Group: Chemistry
Location: On-site South San Francisco, CA
Position Type: Full-time

 

Job Description

Role and Responsibilities

  • Design synthetic routes and strategies to synthesize molecules of interest.
  • Scale up and process development of small molecules across early through late-stage phases
  • Design and conduct control strategies for drug substance manufacturing including impurity identification and synthesis, and fate and purge experiments
  • Purify and characterize molecules with standard analytical techniques (e.g. HPLC, LCMS, NMR)
  • Collaborate with cross functional teams of product development, QA, analytical and formulations.
  • Work with contract organizations and support technology transfer
  • Perform research and/or development in collaboration with others in chemistry and biology; make detailed observations and analyze data.
  • Prepare technical reports, summaries, protocols and quantitative analyses
  • Develop strategies to ensure effective achievement of scientific objectives
  • Exercises independent judgment in selecting methods, techniques and evaluation criteria for obtaining results

Qualifications and Education Requirements

  • PhD in Chemistry with 5+ years or Masters in Chemistry with 10+ years of related experience in pharmaceutical or biotechnology industry or equivalent.
  • Demonstrated expertise and hands-on experience in synthetic organic chemistry, process development and manufacturing.
  • Knowledge of regulatory (ICH, USP etc.) standards.
  • Experience working with CRO/CDMO partners for drug substance manufacturing.
  • Must possess expert knowledge of scientific principles and concepts.
  • A solid understanding of modern analytical techniques (NMR, HPLC, MS)
  • Excellent verbal and written communication skills and the ability to collaborate effectively within a multidisciplinary team

Preferred Skills

  • Able to manage outside vendor collaborations
  • Flexibility and willingness to solve problems that fall outside of immediate area of expertise
  • Work independently in an interdisciplinary, fast-paced, often changing environment.
  • Committed to the values of integrity, accountability, transparency, and drive.

Salary Range: $145,000 to $175,000

If you are interested, please submit a cover letter and your resume to careers@corvuspharma.com